We are actively recruiting postdocs with optics/engineering backgrounds or with biotechnology/synthetic biology backgrounds for 1A and 1B.
0. OVERVIEW
Our mission is to address healthcare unmet needs through the development of new technological concepts and real-world implementations. We are an interdisciplinary team where experts in experimental optics, fluidics, chemistry/materials, information science, and life science/medicine work together to advance invention-driven innovation and scientific discovery.
1a. Tech Dev: Cytometry and microscopy that learns from biology (actively recruiting!)
Data-driven high-content flow cytometry and sorters: Combining optical, fluidic, material, and information technologies, we are developing Learning Cytometers for discoveries, where AI learns from biological data for analysis.
The first “imaging“ cell sorter, by Ghost Cytometry: an image-free approach. Science 2018, eLife 2021, Cell Rep Methods 2024, Stem Cell Rep 2024, Cells 2024, and so on.
The fastest 3D imaging flow cytometer. Cells 2024. Small Science 2022, Biomed Opt Exp 2022, Small Methods 2023
Deep learning-based ultra-rapid nanometry. Nat XX 2025
Temporal flow cytometers, Label-free bacterial spectrometry (coming soon)
Label-free new analysis techniques and sorters are under development (new! Actively recruiting postdocs!)
Microscopy-based live-omics and phenotypic screening technology (new! Actively recruiting postdocs!) Nat Photon 2024, Sci Rep 2014, Small Science 2022
Data analysis platform for developing inferring methods and digital-twin simulator
1B. Tech Dev: networked Pooled system (actively recruiting!)
Networked biophotonics: using unique synthetic multimodal barcoding technologies that can trace a massive number of microcompartments of droplets and hydrogel capsules over time and different instrument for studying single-cells, cell-cell interaction, spheroids/organoids, and material synthesis. Adv Opt Mat 2023, Chem Eur J 2023.
Droplet and hydrogel modules: we routinely use and customize standardized techniques such as droplet generation, fusion, sorting, and various hydrogel structure creations, according to our needs. Sometimes develops our own.
2. biomedical, pharmaceutical and environmental study
Using our high-speed and multimodal measurement platforms, we are addressing previously intractable issues in fields of
Hematology/oncology, immunology, infection, aging
Stem cell research, reproduction medicine
Novel diagnostics technologies
Stem cell research
Microbiology
EVs Anal Chem 2019, Nat Comm 2024.
The biological targets addressed are cells, bacteria, mall particles, their interactions, and XX-oids. These research is driven by biologists in Otalab or with collaborators.
Real-world implementation
Other technologies are in preparation for new start-ups.
Joint research and development with multiple companies is underway.
In cooperation with TECAN Ltd, we automate research and create the next generation of automation technologies.